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Within a few days, P’s agitation lessened and he became happier, more affectionate, and more engaged in his schoolwork. Upon antibiotic discontinuance, his irritability returned, and resumption of treatment helped him regain control. After 6 weeks of treatment, repeat ASO was 791 with an anti-DNAase B titer of 1,090, i.e., basically unchanged. A Cunningham panel to check for evidence of immune dysfunction and antineural antibodies was unremarkable - www.frontiersin.org
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