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Studies have also shown that patients with anxiety- and trauma-related conditions have reduced numbers of regulatory T cells (Tregs, while research also suggests that trauma, illness, or surgery can sensitize certain regions of the brain to mount an inflammatory response to subsequent stressors, which can lead to mood disorders. “There is a robust literature that shows if you induce an inflammatory immune response in people, they quickly show signs of depression and anxiety," says lead author Matthew Frank, Ph.D., a senior research associate in the department of psychology and neuroscience. "Just think about how you feel when you get the flu." - www.genengnews.com